2002: “Clinical case of Encephalic pre hypophysis, peri – chiasmatic Tumor , taken in at the age of 21 years old. The retro - anatomical description , diagnosis within Qifoengraphic method ( Calcan ) , mental Echography. A brief study on the ways of Pituitary body gland Migration”.
Calcan.C, Calcan M. ”New Endocrinology” Research Centre,Buzau,Romania,e-mail:calcan@ buzau.ro ; http://newendocrinology.buzau.ro
A brief embryological,anatomical, and energetical study on the ways of Hypophysis , normal and pathologic justification for migration at the moment of getting ready of the 35 - 50 days of Embryonic Life , and the subsequent consequences “ad vitam”, in the physiopathology of a forced migratory changes:
the Migratory Accompany of the Hypophysis by the Tissular Structures ( cellular groups unreabsorbed melted at the propped moment - as foreign body , a real Branchial Nucleus/solid , strenchtened , the bearer of certain tardive impulses of cellularity D.n.e.s. Feyrter, degenerated subsequenty into fibromas infiltrative towards nalighity , from the first testosteronic 3 – 5 years impuls , and resumed at the age of 15 / 16 /19 years into an invading Encephalic frontal peri - Chiasmatic, pre - hipotalamic, pre - hypophysis Tumor.
Clinical case of perichiasmatic tumor , taken in at the age of 21 years old , with a diffused dissiminated cephalic symptomatology and unique latero cervical adenopaty , diagnosed as Hodgkin disease a Branchial cyst ( the error dg. Anatomo – bioptic ) ,...
Particularly , whose tardive apparition is due to certain embryological Pituitary Migration Accidents ( with artifacts syncytials cells and at peri - tissular ” foreigner ”- nodul ) , in the neighborhood of the left Branchial arch 2 , at the age of 14 – 25 embrionar days old ,...
With the difference of the hypophysis phase (normal) , - stomodeum / cardiac tube primitive - intrasfenoidal towards chiasma , basic prozencephalic , at Departure Moment for Rising migration .
The delay of the migration of a titular tissue with a compact aspect , nodular laid in thenear by neighborhood of the hypophysis the locus “ the Entoblastic Bag ” , the left branchial arch 2 , but ist lead by Migration Command Laws , with the detachment of certain small cells syncytials periphery arise indicial , which are perinodular and taken in embryogenetic Migratory tendency , leads ,...
Recommended Hypophysis on a certain route ; The migration leaves from Stomodeum - faringian which contains the forced and straight crossing ...a tissue layer of supra - faringian Plate and the Route on Prozencefalic ORBIT .
The fascinate Hypophisis through the strong attraction of intraventricular Trigonof the three big crossroad : thalamic – hypotalamic - chiasma through the straight Mammilar formation , the biggest Energetically Lighthouse , at the Limit prozencefalo – faringian , the fascinated force ensured by the tendency of an uncompromised , a vascular bag , on the Carotidian Axe , in growth and expand , a cause which is necessary for the oxygenation , in spurt artesian permanent.
The origin of portal system brought informationality / Permutated coelomic-vitelinic , through carotidal crossroad and stronger by the starting of migration with the portal -hypophysis axe , these produce ,the covering of the way , and some - time accessory bringing of a tisulare cluster perinodular , which are not suffering the “ atrofiation compromise ”an initiation procedure of remainders , as remaind -iritativ , Compressive Tumor .
It isn’t choosing the way of final settlement through the melt of a real “ strange thing ”( we take here the notion of “remained embryological artifact” ) .
Even if the restant nodule can’t resist to the migration command of the commanding body of migration and execute the satellite attraction of sinticial neighbourhood .
It isn’t helped to escape , it will ended stocked somewhere on the way , most probably in the intermediate area peri - faringian, where “ it will sleep ” passing the irritating endocrine resuscitation of the teenage, but… it could become active , uncooperative , irritating very sudden .
Unsuccessful , undesired bag ( of left indicial cells in migratory current) , tiny and maybe transported , through the migration’s blow of very strong partner for themselves ,hypophysis , cove red by mirage of attraction and so brought power ….. the gem charge of confluentorderly , connection multi - hyper - informational of portal system – which is more and more , stocked hypophysis as in a strong box… and passed for the encephalic , on a key position:
between the “ fascicular lighthouse ” of the mamilar formation ( tied through tegument roll by hipocamp – limbic ) and chiasmatic and ventricular embrace .
Another veritable complex , as the real embryological commander of migrations ( which is superpose on the top of the one from above , but not benefiting of the experiences energetically ).
The faringian - stomodeum aria, initiatory of the proximity primitive, superior, cranial intestine as commanding accessory of perichard , preheart primitive heart - tube ( placoda perichard mezotelial ) , placoidial epithelium , olfactive place( the fourth week ) or preheart collar.
All these are ancestral blocks of evolutive initiation supra - specialized, so called precordal-cranian-cartilaginos lever of the second phase:
condrocranios – craniums cartilaginous which has a similar phase - ichtiosaurieni ( fish ) , they become collars - forks for the pituitary hole (melting in the unic cartilaginous place , the based collar, basilar adjacent with etmoidal bone and together formed the pituitary hole .
Here, it will be receive the pituitary bag, the nest of the future gland, in fact a protection area, extremely good, with a future hole towards the ordered and wished connection, even more presumptive for future.
In our clinical study, the strange tissulare, cells bag , peri – pituitary , it remains constant functional , on a long way of time , endocrine and vascular impulses which were monopolize occasionally , started the procedure of growth and functionality looking for a place without any commander frame of program.
This expand chaotic work , the simple way of responding at the commander’s rules , received and interpretated functional - anatomic disordered.
It isn’t allowed the local evolution , without ordered control , capacities , and solicitant connections.
The compressive , anarchic growth , the setup simple , global tissular and infiltrative, where it tries the insinuation proposed by auto - vascularisation.
In this case , it is and will be a large expansion , more and more compressive by the secretor function.